MRPL40 antibody (Middle Region)

Catalog No. ABIN2789157

The Rabbit Polyclonal anti-MRPL40 antibody is suitable to detect MRPL40 in samples from Human, Rat, Mouse, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for MRPL40 antibody (Middle Region) (ABIN2789157)

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL40 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL40 Antibody

Binding Specificity: Middle Region

Purpose: MRPL40 Antibody - middle region

Sequence: TPLKFLDKAR ERPQVELTFE ETERRALLLK KWSLYKQQER KMERDTIRAM

Predicted Reactivity: Guinea Pig: 77%, Horse: 79%, Human: 100%, Mouse: 75%, Rabbit: 77%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against MRPL40. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62476-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL40

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Alternative Name: MRPL40

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

Gene Name: Mitochondrial ribosomal protein L40

Alternative Symbols: URIM, L40mt, NLVCF, MRPL22, MRP-L22, MRP-L40

Protein Name: Replication protein A 32 kDa subunit

Molecular Weight: 23kDa

Gene ID: 64976

NCBI Accession: NP_002937

UniProt: P15927