ARHGEF1 antibody (N-Term)
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- Target See all ARHGEF1 Antibodies
- ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Pig, Cow, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARHGEF1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SAAVVNAIGL YMRHLGVRTK SGDKKSGRNF FRKKVMGNRR SDEPAKTKKG
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against ARHGEF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGEF1
- Top Product
- Discover our top product ARHGEF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 912 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))
- Alternative Name
- ARHGEF1 (ARHGEF1 Products)
- Synonyms
- arhgef1 antibody, cb473 antibody, zgc:158261 antibody, ARHGEF1 antibody, GEF1 antibody, LBCL2 antibody, LSC antibody, P115-RHOGEF antibody, SUB1.5 antibody, Lbcl2 antibody, Lsc antibody, Rho guanine nucleotide exchange factor (GEF) 1a antibody, Rho guanine nucleotide exchange factor 1 antibody, Rho guanine nucleotide exchange factor (GEF) 1 antibody, arhgef1a antibody, ARHGEF1 antibody, arhgef1 antibody, Arhgef1 antibody
- Background
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: GEF1, LBCL2, LSC, P115-RHOGEF, SUB1.5
Protein Interaction Partner: TCF4, UBC, CYFIP1, CAP2, FN1, DCUN1D1, SH3KBP1, CSNK1E, SREBF2, MEPCE, TAF10, CNKSR1, GNA13, ARHGEF1, PRKCA, CD44, RAP1A, HRAS, PIK3CA, RHOA, GNA12, ATR,
Protein Size: 912 - Molecular Weight
- 102 kDa
- Gene ID
- 9138
- NCBI Accession
- NM_199002, NP_945353
- UniProt
- Q92888
- Pathways
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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