ARHGEF1 antibody (N-Term)

Catalog No. ABIN2789444

The Rabbit Polyclonal anti-ARHGEF1 antibody (ABIN2789444) specifically detects ARHGEF1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse and Pig samples.

Quick Overview for ARHGEF1 antibody (N-Term) (ABIN2789444)

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARHGEF1 Antibody

Binding Specificity: N-Term

Purpose: ARHGEF1 Antibody - N-terminal region

Sequence: SAAVVNAIGL YMRHLGVRTK SGDKKSGRNF FRKKVMGNRR SDEPAKTKKG

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ARHGEF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGEF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63316-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Alternative Name: ARHGEF1

Background:

Background Information: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Gene Name: Rho guanine nucleotide exchange factor (GEF) 1

Alternative Symbols: LSC, GEF1, IMD62, LBCL2, SUB1.5, P115-RHOGEF

Protein Name: Rho guanine nucleotide exchange factor 1

Molecular Weight: 102kDa

Gene ID: 9138

NCBI Accession: NP_945353

UniProt: Q92888

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling