Cyclin B2 antibody (N-Term)

Catalog No. ABIN2789489

Product Details anti-Cyclin B2 Antibody

Target: Cyclin B2 (CCNB2)

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin B2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IGNRVTTRAA QVAKKAQNTK VPVQPTKTTN VNKQLKPTAS VKPVQMEKLA

Predicted Reactivity: Cow: 83%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against CCNB2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 398 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin B2

Target: Cyclin B2 (CCNB2)

Alternative Name: CCNB2 (CCNB2 Products)

Synonyms: HsT17299 antibody, CycB2 antibody, sb:cb303 antibody, cycB2 antibody, LOC100136691 antibody, C-B2 antibody, cyclinb2 antibody, hst17299 antibody, LOC100282653 antibody, cyclin B2 antibody, cyclin B2 S homeolog antibody, CCNB2 antibody, Ccnb2 antibody, ccnb2 antibody, LOC100136691 antibody, LOC100282653 antibody, ccnb2.S antibody

Background: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Alias Symbols: HsT17299
Protein Interaction Partner: CKS2, CKS1B, CDK1, CDK2, MCM2, CDKN1A, ATR, UBC, tat, TSPYL2, TGFBR2,
Protein Size: 398

Molecular Weight: 45 kDa

Gene ID: 9133

NCBI Accession: NM_004701, NP_004692

UniProt: O95067

Pathways: Cell Division Cycle, M Phase