IL13 Receptor alpha 1 antibody (N-Term)

Catalog No. ABIN2789491

Product Details anti-IL13 Receptor alpha 1 Antibody

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Pig, Sheep, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL13 Receptor alpha 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VSVENLCTVI WTWNPPEGAS SNCSLWYFSH FGDKQDKKIA PETRRSIEVP

Predicted Reactivity: Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 86%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against IL13RA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of IL13RA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 427 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Alternative Name: IL13RA1 (IL13RA1 Products)

Synonyms: CD213A2 antibody, CT19 antibody, IL-13R antibody, IL13BP antibody, CD213A1 antibody, IL-13Ra antibody, NR4 antibody, AI882074 antibody, CD213a1 antibody, IL-13r[a] antibody, Il13ra antibody, IL13RA1 antibody, il-13ra1 antibody, si:ch211-150g2.2 antibody, interleukin 13 receptor subunit alpha 2 antibody, interleukin 13 receptor subunit alpha 1 antibody, interleukin 13 receptor, alpha 1 antibody, interleukin 13 receptor, alpha 1-like antibody, IL13RA2 antibody, IL13RA1 antibody, Il13ra1 antibody, il13ra1 antibody, LOC100360218 antibody

Background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Alias Symbols: CD213A1, IL-13Ra, NR4
Protein Interaction Partner: UBC, IL2RG, TMEM39B, ELAVL1, TRAF3IP1, DLG4, TYK2, IL4R, IL13,
Protein Size: 427

Molecular Weight: 47 kDa

Gene ID: 3597

NCBI Accession: NM_001560, NP_001551

UniProt: P78552

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response