EZR-ROS1 (C-Term) antibody

Catalog No. ABIN2789629

Product Details

Target: EZR-ROS1

Binding Specificity: C-Term

Reactivity: Dog, Horse, Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Sequence: EGLNYMVLAT ECGQGEEKSE GPLGSQESES CGLRKEEKEP HADKDFCQEK

Predicted Reactivity: Dog: 86%, Horse: 86%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against EZR-ROS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ROS1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: EZR-ROS1

Background: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.
Alias Symbols: ROS, MCF3, c-ros-1
Protein Size: 858

Molecular Weight: 94 kDa

Gene ID: 6098

NCBI Accession: NM_002944, NP_002935

UniProt: P08922