NEIL1 antibody (C-Term)

Catalog No. ABIN2789640

This anti-NEIL1 antibody is a Rabbit Polyclonal antibody detecting NEIL1 in WB. Suitable for Human and Pig.

Quick Overview for NEIL1 antibody (C-Term) (ABIN2789640)

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEIL1 Antibody

Binding Specificity: C-Term

Sequence: SLQDRHGRTI WFQGDPGPLA PKGRKSRKKK SKATQLSPED RVEDALPPSK

Predicted Reactivity: Human: 100%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against NEIL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 390 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEIL1

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Alternative Name: NEIL1

Background: NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Alias Symbols: FLJ22402, FPG1, NEI1, hFPG1
Protein Interaction Partner: APP, MYC, XRCC1, LIG3, POLB,
Protein Size: 390

Molecular Weight: 44 kDa

Gene ID: 79661

NCBI Accession: NM_024608, NP_078884

UniProt: Q96FI4

Pathways: DNA Damage Repair