GPBAR1 antibody (C-Term)
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- Target See all GPBAR1 Antibodies
- GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GPBAR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AAAVPVAMGL GDQRYTAPWR AAAQRCLQGL WGRASRDSPG PSIAYHPSSQ
- Predicted Reactivity
- Human: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GPBAR1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GPBAR1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 330 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
- Alternative Name
- GPBAR1 (GPBAR1 Products)
- Synonyms
- BG37 antibody, GPCR19 antibody, GPR131 antibody, M-BAR antibody, TGR5 antibody, Tgr5 antibody, MGC84403 antibody, GPBAR1 antibody, Gpbar1 antibody, GPCR antibody, G protein-coupled bile acid receptor 1 antibody, G protein-coupled bile acid receptor 1 S homeolog antibody, GPBAR1 antibody, Gpbar1 antibody, gpbar1.S antibody
- Background
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This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Alias Symbols: BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5
Protein Size: 330 - Molecular Weight
- 35 kDa
- Gene ID
- 151306
- NCBI Accession
- NM_170699, NP_733800
- UniProt
- Q8TDU6
- Pathways
- WNT Signaling, Hormone Transport, Sensory Perception of Sound
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