NEIL2 antibody (N-Term)

Catalog No. ABIN2789787

This Rabbit Polyclonal antibody specifically detects NEIL2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for NEIL2 antibody (N-Term) (ABIN2789787)

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEIL2 Antibody

Binding Specificity: N-Term

Sequence: GDAGRWLRVS FGLFGSVWVN DFSRAKKANK RGDWRDPSPR LVLHFGGGGF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NEIL2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 271 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEIL2

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Alternative Name: NEIL2

Background: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Alias Symbols: FLJ31644, MGC2832, MGC4505, NEH2, NEI2
Protein Interaction Partner: TRIM27, REL, MEOX1, UBC, ELAVL1, KEAP1, EP300,
Protein Size: 271

Molecular Weight: 30 kDa

Gene ID: 252969

NCBI Accession: NM_001135747, NP_001129219

Pathways: DNA Damage Repair