NEIL2 antibody

Catalog No. ABIN933141

Product Details anti-NEIL2 Antibody

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEIL2 antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: NEIL2 antibody was raised in mouse using recombinant Human Nei Like 2 (E. Coli)

Clone: 2626C2a

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: NEIL2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for NEIL2

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Alternative Name: NEIL2 (NEIL2 Products)

Synonyms: NEH2 antibody, NEI2 antibody, Gm1212 antibody, nei like DNA glycosylase 2 antibody, nei like 2 (E. coli) antibody, NEIL2 antibody, Neil2 antibody

Background: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. Synonyms: Monoclonal NEIL2 antibody, Anti-NEIL2 antibody, Nei endonuclease VIII-like 2 antibody, NEH2 antibody, MGC2832 antibody, MGC4505 antibody, FLJ31644 antibody.

Pathways: DNA Damage Repair