ATG13 antibody (N-Term)

Catalog No. ABIN2789823

Product Details anti-ATG13 Antibody

Target: ATG13 (Autophagy Related 13 (ATG13))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MCVEISLKTS EGDSMELEIW CLEMNEKCDK EIKVSYTVYN RLSLLLKSLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ATG13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATG13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 480 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATG13

Target: ATG13 (Autophagy Related 13 (ATG13))

Alternative Name: ATG13 (ATG13 Products)

Synonyms: zgc:63526 antibody, KIAA0652 antibody, PARATARG8 antibody, 1110053A20Rik antibody, D2Ertd391e antibody, Harbi1 antibody, Harbi1l antibody, RGD1310685 antibody, autophagy related 13 antibody, ATG13 autophagy related 13 homolog (S. cerevisiae) antibody, ATG13 antibody, atg13 antibody, Atg13 antibody

Background: ATG13 is an autophagy factor required for autophagosome formation. ATG13 is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
Alias Symbols: ATG13, FLJ20698, KIAA0652
Protein Interaction Partner: SESN2, ATG16L1, MAP1LC3A, ATG101, GABARAP, AMBRA1, ULK1, APP, MAP1LC3C, TAB3, MAP1LC3B, GABARAPL1, TAB2, GABARAPL2, UBC, RB1CC1,
Protein Size: 480

Molecular Weight: 53 kDa

Gene ID: 9776

NCBI Accession: NM_014741, NP_055556

UniProt: O75143

Pathways: PI3K-Akt Signaling, Autophagy