GIGYF2 antibody (AA 1071-1120)

Catalog No. ABIN7230588

The Rabbit Polyclonal anti-GIGYF2 antibody (ABIN7230588) specifically detects GIGYF2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GIGYF2 antibody (AA 1071-1120) (ABIN7230588)

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIGYF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GIGYF2 Antibody

Binding Specificity: AA 1071-1120

Purpose: Rabbit Anti-PERQ2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PERQ2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PERQ2 protein at AA range: 1071-1120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GIGYF2

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Alternative Name: PERQ2

Background: GRB10-interacting GYF protein 2, PERQ amino acid-rich with GYF domain-containing protein 2, Trinucleotide repeat-containing gene 15 proteinGIGYF2 contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. GIGYF2 is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in GIGYF2 were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.

Molecular Weight: 142kD

Gene ID: 26058

UniProt: Q6Y7W6

Pathways: Feeding Behaviour, SARS-CoV-2 Protein Interactome