NPR3 antibody (C-Term)

Catalog No. ABIN2789944

The Rabbit Polyclonal anti-NPR3 antibody is suitable to detect NPR3 in samples from Human, Rat, Mouse, Cow, Dog, Horse, Rabbit and Pig. It has been validated for WB.

Quick Overview for NPR3 antibody (C-Term) (ABIN2789944)

Target: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPR3 Antibody

Binding Specificity: C-Term

Purpose: NPR3 Antibody - C-terminal region

Sequence: LEESAVTGIV VGALLGAGLL MAFYFFRKKY RITIERRTQQ EESNLGKHRE

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against NPR3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64738-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPR3

Target: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Alternative Name: NPR3

Background:

Background Information: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

Alternative Symbols: NPRC, ANP-C, ANPRC, NPR-C, ANPR-C, GUCY2B, C5orf23

Protein Name: Atrial natriuretic peptide receptor 3 Ensembl ENSP00000402490

Molecular Weight: 37kDa

Gene ID: 4883

NCBI Accession: NP_001191305

UniProt: E7EPG9

Pathways: cAMP Metabolic Process