PPP3CC antibody (C-Term)

Catalog No. ABIN2789946

The Rabbit Polyclonal anti-PPP3CC antibody (ABIN2789946) specifically detects PPP3CC in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for PPP3CC antibody (C-Term) (ABIN2789946)

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP3CC Antibody

Binding Specificity: C-Term

Sequence: FTEPPAFGPV CDLLWSDPSE DYGNEKTLEH YTHNTVRGCS YFYSYPAVCE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PPP3CC. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Alternative Name: PPP3CC

Background: Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CALNA3, CNA3, PP2Bgamma
Protein Interaction Partner: AMPH, PRKAR2A, THAP7, ITPKC, HAX1, UBC, SDC2, CSNK2B, BCL2, APP, MLH1, CABIN1, BMPR1B, TGFBR1,
Protein Size: 326

Molecular Weight: 35 kDa

Gene ID: 5533

NCBI Accession: NM_001243974

UniProt: G3V111

Pathways: RTK Signaling, WNT Signaling, VEGF Signaling, BCR Signaling