HRH2 antibody (C-Term)

Catalog No. ABIN2790187

The Rabbit Polyclonal anti-HRH2 antibody (ABIN2790187) specifically detects HRH2 in WB. The antibody is reactive with Human, Rat, Dog and Horse samples.

Quick Overview for HRH2 antibody (C-Term) (ABIN2790187)

Target: HRH2 (Histamine Receptor H2 (HRH2))

Reactivity: Human, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HRH2 Antibody

Binding Specificity: C-Term

Purpose: HRH2 Antibody - C-terminal region

Sequence: DFRTGYQQLF CCRLANRNSH KTSLRSNASQ LSRTQSREPR QQEEKPLKLQ

Predicted Reactivity: Dog: 77%, Horse: 79%, Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against HRH2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HRH2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65575-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRH2

Target: HRH2 (Histamine Receptor H2 (HRH2))

Alternative Name: HRH2

Background:

Background Information: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Histamine receptor H2

Alternative Symbols: H2R, HH2R

Protein Name: Histamine H2 receptor

Molecular Weight: 40kDa

Gene ID: 3274

NCBI Accession: NP_071640

UniProt: P25021