HRH2 antibody (C-Term)

Catalog No. ABIN2790187

Product Details anti-HRH2 Antibody

Target: HRH2 (Histamine Receptor H2 (HRH2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DFRTGYQQLF CCRLANRNSH KTSLRSNASQ LSRTQSREPR QQEEKPLKLQ

Predicted Reactivity: Dog: 77%, Horse: 79%, Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against HRH2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HRH2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 359 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRH2

Target: HRH2 (Histamine Receptor H2 (HRH2))

Alternative Name: HRH2 (HRH2 Products)

Synonyms: H2R antibody, HH2R antibody, HRH2 antibody, histamine receptor H2 antibody, histamine receptor H2a antibody, histamine receptor H 2 antibody, HRH2 antibody, Hrh2 antibody, hrh2a antibody

Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: H2R
Protein Interaction Partner: GPRASP2, GPRASP1,
Protein Size: 359

Molecular Weight: 40 kDa

Gene ID: 3274

NCBI Accession: NM_022304, NP_071640

UniProt: P25021