SH2D4A antibody (N-Term)

Catalog No. ABIN2790377

Product Details anti-SH2D4A Antibody

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D4A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IWKKVAEKEE LEQGSRPAPT LEEEKIRSLS SSSRNIQQML ADSINRMKAY

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SH2D4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SH2D4A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 454 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH2D4A

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Alternative Name: SH2D4A (SH2D4A Products)

Synonyms: SH2D4A antibody, sh2a antibody, PPP1R38 antibody, SH2A antibody, 2210402M20Rik antibody, SH2 domain containing 4A antibody, SH2D4A antibody, sh2d4a antibody, Sh2d4a antibody

Background: SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. SH2D4A may play a role in T-cell development and function.
Alias Symbols: FLJ20967, SH2A, PPP1R38
Protein Interaction Partner: CCDC172, NUTM1, KRT40, FSD2, UBXN11, LZTS2, USHBP1, CEP70, CEP76, HMBOX1, RINT1, NECAB2, DBNL, TFIP11, LDOC1, MTUS2, NINL, SPAG5, IKZF1, STAM2, SORBS3, PDE4DIP, PSTPIP1, STX11, SKAP1, CASK, SORBS2, ZBTB16, TRAF2, TACC1, SH3GL1, VPS52, TRIM27, PPP1CB, MAGE
Protein Size: 454

Molecular Weight: 53 kDa

Gene ID: 63898

NCBI Accession: NM_022071, NP_071354

UniProt: Q9H788