MRPL41 antibody (C-Term)

Catalog No. ABIN2790422

Product Details anti-MRPL41 Antibody

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL41 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ESEETPLTAA QLFSEAVAPA IEKDFKDGTF DPDNLEKYGF EPTQEGKLFQ

Predicted Reactivity: Cow: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MRPL41. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPL41

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 137 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Alternative Name: MRPL41 (MRPL41 Products)

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family.
Alias Symbols: BMRP, MRP-L27, MRPL27, PIG3, RPML27
Protein Interaction Partner: TRIM63, TRIM55, TP53, SOX2, MRPL55, MRPL10, MRPL52, MRPL44, MRPS9, TSR1, MRPL51, MRPL37, MRPL13, MRPL42, MRPS28, MRPL3, HNRNPA0, MRPL28, FAM3C, FUBP1, MRPL12, MRPL23, ABCD3, PLP2, OGDH, NONO, ILF3, ICT1, CAND1, UBC,
Protein Size: 137

Molecular Weight: 15 kDa

Gene ID: 64975

NCBI Accession: NM_032477, NP_115866

UniProt: Q8IXM3

Pathways: p53 Signaling