MICU1 antibody (C-Term)

Catalog No. ABIN2790523

Product Details anti-MICU1 Antibody

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Zebrafish (Danio rerio), Horse, Goat, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICU1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSDHVCDVVF ALFDCDGNGE LSNKEFVSIM KQRLMRGLEK PKDMGFTRLM

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MICU1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MICU1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 278 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MICU1

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Alternative Name: MICU1 (MICU1 Products)

Background: MICU1 is a key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. It may act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. MICU1 induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
Alias Symbols: CALC, DKFZp564C246, EFHA3, FLJ12684, CBARA1
Protein Interaction Partner: UBC, APP, BABAM1,
Protein Size: 278

Molecular Weight: 30 kDa

Gene ID: 10367

NCBI Accession: NM_001195519, NP_001182448

UniProt: Q9BPX6