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MICU1 antibody

MICU1 Reactivity: Human, Rat, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7252387
  • Target See all MICU1 Antibodies
    MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
    Reactivity
    • 32
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 24
    • 8
    • 1
    Rabbit
    Clonality
    • 26
    • 7
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MICU1 antibody is un-conjugated
    Application
    • 23
    • 13
    • 4
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human MICU1
    Isotype
    IgG
    Top Product
    Discover our top product MICU1 Primary Antibody
  • Application Notes
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
    Alternative Name
    MICU1 (MICU1 Products)
    Synonyms
    CALC antibody, CBARA1 antibody, EFHA3 antibody, C730016L05Rik antibody, Calc antibody, Cbara1 antibody, mitochondrial calcium uptake 1 antibody, MICU1 antibody, Micu1 antibody
    Background
    This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
    UniProt
    Q9BPX6
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