CDK9 antibody (N-Term)
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- Target See all CDK9 Antibodies
- CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Pig, Dog, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK9 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PFCDEVSKYE KLAKIGQGTF GEVFKARHRK TGQKVALKKV LMENEKEGFP
- Predicted Reactivity
- Cow: 92%, Dog: 100%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 92%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against CDK9. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDK9
- Top Product
- Discover our top product CDK9 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
- Alternative Name
- CDK9 (CDK9 Products)
- Synonyms
- C-2k antibody, CDC2L4 antibody, CTK1 antibody, PITALRE antibody, TAK antibody, wu:fb22e09 antibody, wu:fc06c02 antibody, c-2k antibody, cdc2l4 antibody, cdk9 antibody, ctk1 antibody, pitalre antibody, tak antibody, CDK9 antibody, CG5179 antibody, Dmel\\CG5179 antibody, P-TEF antibody, P-TEFb antibody, PTefb antibody, cyclin dependent kinase 9 antibody, cyclin-dependent kinase 9 (CDC2-related kinase) antibody, cyclin-dependent kinase 9 L homeolog antibody, cyclin-dependent kinase 9 antibody, Cyclin-dependent kinase 9 antibody, cyclin-dependent kinase 9 S homeolog antibody, CDK9 antibody, cdk9 antibody, cdk9.L antibody, Cdk9 antibody, cdk9.S antibody
- Background
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CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Alias Symbols: RP11-228B15.5, C-2k, CDC2L4, PITALRE, TAK, CTK1
Protein Interaction Partner: UBC, MEPCE, tat, LARP7, BRD4, CCNT1, ATM, SUMO2, AFF1, HEXIM1, FKBP5, RNF20, MSL2, RNF40, HIST2H2BE, POLR2A, MSL1, CDK9, SMC2, PLEC, CCAR2, SMC4, STIP1, MLLT3, MLLT1, CDK12, AFF4, FGFR1, CCNT2, AFF3, FBXO25, CUL1, SKIV2L, ATP1A1, SUPT5H, RPS4X, RN7SK, HEX
Protein Size: 372 - Molecular Weight
- 43 kDa
- Gene ID
- 1025
- NCBI Accession
- NM_001261, NP_001252
- UniProt
- P50750
- Pathways
- Cell Division Cycle
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