NFIC antibody (C-Term)

Catalog No. ABIN2792601

There is 1 publication for this product available. The Rabbit Polyclonal anti-NFIC antibody is suitable to detect NFIC in samples from Human. It has been validated for WB.

Quick Overview for NFIC antibody (C-Term) (ABIN2792601)

Target: NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFIC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NFIC Antibody

Binding Specificity: C-Term

Purpose: NFIC Antibody - C-terminal region

Sequence: VRERDAEQSG SPRTGMGSDQ EDSKPITLDT TDFQESFVTS GVFSVTELIQ

Cross-Reactivity: Human

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NFIon Channel. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFIC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-NFIC antibody (ABIN2792601)

Liang, Tikhanovich, Nasheuer, Folk: "Stimulation of BK virus DNA replication by NFI family transcription factors." in: Journal of virology, Vol. 86, Issue 6, pp. 3264-75, (2012) (PubMed).

Target Details for NFIC

Target: NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC))

Alternative Name: NFIC

Background:

Background Information: Brg- or hBrm-associated factor (BAF) complexes, a chromatin-remodeling complex family of mammalian cells, facilitate transcriptional activity by remodeling nucleosome structure. Brg1 is the core subunit of Brg-associated factor complexes. BAF complexes can interact with NF1/CTF and RNAP II, and this interaction is closely dependent on the activation of gene transcription.

Gene Name: Nuclear factor I/C (CCAAT-binding transcription factor)

Alternative Symbols: CTF, NFI, CTF5, NF-I

Protein Name: Nuclear factor 1 C-type

Molecular Weight: 48kDa

Gene ID: 4782

NCBI Accession: NP_005588

UniProt: P08651