MLLT1 antibody (C-Term)

Catalog No. ABIN2794822

Product Details anti-MLLT1 Antibody

Target: MLLT1 (MLLT1, super elongation complex subunit (MLLT1))

Binding Specificity: AA 523-552, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLLT1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human MLLT1 (C-term) Antibody

Immunogen: This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-MLLT1 Pab was detected using the purified Pab.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MLLT1

Target: MLLT1 (MLLT1, super elongation complex subunit (MLLT1))

Alternative Name: MLLT1 (MLLT1 Products)

Synonyms: MGC84026 antibody, MLLT1 antibody, ENL antibody, LTG19 antibody, YEATS1 antibody, AA407901 antibody, BAM11 antibody, MLLT1, super elongation complex subunit antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antibody, Mllt1 antibody, MLLT1 antibody, mllt1.L antibody, mllt1 antibody

Background:

Target Description: Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.

Gene Symbol: MLLT1

Molecular Weight: 62056 Da

Gene ID: 4298

UniProt: Q03111