Retinoic Acid Early Transcript 1E (RAET1E) (AA 150-179), (Center) antibody

Catalog No. ABIN2795781

Product Details

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Binding Specificity: AA 150-179, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human RAET1E(Center) Antibody

Immunogen: This RAET1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the Central region of human RAET1E.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000RAET1E Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Alternative Name: RAET1E (RAET1E Products)

Synonyms: LETAL antibody, N2DL-4 antibody, NKG2DL4 antibody, RAET1E2 antibody, RL-4 antibody, ULBP4 antibody, bA350J20.7 antibody, retinoic acid early transcript 1E antibody, RAET1E antibody, Raet1e antibody

Background:

Target Description: Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1, MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand for NKG2D (KLRK1, MIM 611817), which is expressed on the surface of several types of immune cells and is involved in innate and adaptive immune responses (summary by Radosavljevic et al. (2002) [PubMed 11827464] and Cao et al. (2007) [PubMed 17470428]).

Gene Symbol: RAET1E

Molecular Weight: 30122 Da

Gene ID: 135250

UniProt: Q8TD07