DAZ4 antibody (Center)

Catalog No. ABIN2797811

Product Details anti-DAZ4 Antibody

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Binding Specificity: AA 90-119, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human DAZ4 (Center) Antibody

Immunogen: This DAZ4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human DAZ4.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50DAZ4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for DAZ4

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Alternative Name: DAZ4 (DAZ4 Products)

Synonyms: pDP1680 antibody, pDP1681 antibody, DAZ4 antibody, deleted in azoospermia 4 antibody, DAZ4 antibody

Background:

Target Description: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Gene Symbol: DAZ4

Molecular Weight: 64785 Da

Gene ID: 57135

UniProt: Q86SG3