POF1B antibody (Center)
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- Target See all POF1B Antibodies
- POF1B (Premature Ovarian Failure, 1B (POF1B))
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Binding Specificity
- AA 337-366, Center
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POF1B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Mouse POF1B (Center) Antibody
- Immunogen
- This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product POF1B Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000POF1B Antibody (Center) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- POF1B (Premature Ovarian Failure, 1B (POF1B))
- Alternative Name
- POF1B (POF1B Products)
- Synonyms
- RGD1560798 antibody, 2310066B14Rik antibody, POF antibody, POF2B antibody, POF1B, actin binding protein antibody, premature ovarian failure 1B antibody, Pof1b antibody, POF1B antibody
- Background
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Target Description: Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called 'POF1' and 'POF2' have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
Gene Symbol: POF1B
- Molecular Weight
- 68065 Da
- Gene ID
- 79983
- UniProt
- Q8WVV4
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