CDCA8 antibody (Center)

Catalog No. ABIN2798608

This Rabbit Polyclonal antibody specifically detects CDCA8 in WB, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for CDCA8 antibody (Center) (ABIN2798608)

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CDCA8 Antibody

Binding Specificity: AA 115-144, Center

Purpose: Rabbit Anti-Human CDCA8 (Center) Antibody

Immunogen: This CDCA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the Central region of human CDCA8.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of CDCA8 Antibody (Center) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Alternative Name: CDCA8

Background:

Target Description: CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.

Gene Symbol: CDCA8

Molecular Weight: 31323 Da

Gene ID: 55143

UniProt: Q53HL2

Pathways: Cell Division Cycle, M Phase