RUNX3 antibody (Center)

Catalog No. ABIN2798697

This anti-RUNX3 antibody is a Rabbit Polyclonal antibody detecting RUNX3 in WB, IHC and IF. Suitable for Human.

Quick Overview for RUNX3 antibody (Center) (ABIN2798697)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RUNX3 Antibody

Binding Specificity: AA 168-197, Center

Purpose: Rabbit Anti-Human RUNX3 (Center) Antibody

Immunogen: This RUNX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human RUNX3.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50Western blot analysis of lysates from HL-60, Jurkat cell line (from left to right), using RUNX3 Antibody (Center) . RUNX3 immunoreactivity is localized to Nucleus and Cytoplasm significantly.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3

Background:

Target Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Symbol: RUNX3

Molecular Weight: 44356 Da

Gene ID: 864

UniProt: Q13761