GJB4 antibody (N-Term)

Catalog No. ABIN2798869

Product Details anti-GJB4 Antibody

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Binding Specificity: AA 90-120, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human Connexin 30.3 (N-term) Antibody

Immunogen: This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of GJB4 (arrow) using rabbit polyclonal GJB4 Antibody (H105.Connexin) with the GJB4 gene.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.570 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for GJB4

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Alternative Name: Connexin 30.3 (GJB4 Products)

Synonyms: GJB4 antibody, Cnx30.3 antibody, Cx30.3 antibody, Gjb-4 antibody, CX30.3 antibody, EKV antibody, gap junction protein beta 4 antibody, gap junction protein, beta 4 antibody, GJB4 antibody, Gjb4 antibody

Background:

Target Description: Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.

Gene Symbol: GJB4

Molecular Weight: 30419 Da

Gene ID: 127534

UniProt: Q9NTQ9