CD45 antibody (AA 451-550)
Quick Overview for CD45 antibody (AA 451-550) (ABIN2808375)
Target
See all CD45 (PTPRC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 451-550
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Cross-Reactivity
- Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse CD45
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Isotype
- IgG
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC Reactivity: Human, Dog FACS, IHC, WB, StM Host: Mouse Monoclonal 2B11-PD7-26 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibodyPTPRC Reactivity: Human FACS, WB, IP, IHC (p), ICC Host: Mouse Monoclonal MEM-28 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 193-575) antibodyPTPRC Reactivity: Human IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 371-556) antibodyPTPRC Reactivity: Mouse IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) antibodyPTPRC Reactivity: Human FACS, IHC, WB, IF, ELISA Host: Mouse Monoclonal 17H9D4 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibodyPTPRC Reactivity: Human, Mouse, Rat, Dog, Chicken, Cow, Cat, Rabbit, Sheep, Guinea Pig, Pig, Goat, Monkey, Horse, Hamster, Donkey, Avian WB, IHC (p), IHC (fro) Host: Goat Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibodyPTPRC Reactivity: Human, Mouse, Rat FACS, IHC, WB, ELISA, ICC Host: Mouse Monoclonal 2H3E2 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibodyPTPRC Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 1B9B10 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 928-989) antibodyPTPRC Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 5D3A3 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibodyPTPRC Reactivity: Human FACS, IHC, WB, IF, StM Host: Rabbit Monoclonal PTPRC-2877R unconjugated Recombinant Antibody
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Application Notes
- FCM 1:20-100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
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Alternative Name
- CD45
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Background
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Synonyms: Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Lymphocyte antigen 5, L-CA, Ly-5, T200
Background: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.
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UniProt
- P06800
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
Target
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