CNOT11 antibody (Alexa Fluor 594)

Catalog No. ABIN2810792

Product Details anti-CNOT11 Antibody (Alexa Fluor 594)

Target: CNOT11 (CCR4-NOT Transcription Complex, Subunit 11 (CNOT11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT11 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf29

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CNOT11

Target: CNOT11 (CCR4-NOT Transcription Complex, Subunit 11 (CNOT11))

Alternative Name: C2orf29 (CNOT11 Products)

Synonyms: C2orf29 antibody, 2410015L18Rik antibody, C40 antibody, D1Bwg0212e antibody, RGD1560909 antibody, fj49e01 antibody, wu:fj49e01 antibody, zgc:163002 antibody, CCR4-NOT transcription complex subunit 11 antibody, CCR4-NOT transcription complex, subunit 11 antibody, CNOT11 antibody, Cnot11 antibody, cnot11 antibody

Background:

Synonyms: C2orf29, C40, CB029_HUMAN, Chromosome 2 open reading frame 29, Hypothetical protein LOC55571, UPF0760 protein C2orf29.

Background: C2orf29, also known as C40, is a 510 amino acid protein that belongs to the UPF0760 family and is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Gene ID: 55571