EpCAM antibody (AA 221-314) (AbBy Fluor® 594)

Catalog No. ABIN2812832

The AbBy Fluor® 594-conjugated Rabbit Polyclonal anti-EpCAM antibody (ABIN2812832) specifically detects EpCAM in WB, FACS, IF (p) and IF (cc). The antibody is reactive with Human samples.

Quick Overview for EpCAM antibody (AA 221-314) (AbBy Fluor® 594) (ABIN2812832)

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EpCAM antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-EpCAM Antibody (AbBy Fluor® 594)

Binding Specificity: AA 221-314

Purpose: EpCAM Polyclonal Antibody, AbBy Fluor-594 Conjugated

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EpCAM

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EpCAM

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Alternative Name: EpCAM/ CD326

Background:

Synonyms: ESA, KSA, M4S1, MK-1, DIAR5, EGP-2, EGP4, KS1/4, MIC18, TROP1, EGP314, HNPCC8, TACSTD1, Epithelial cell adhesion molecule, Ep-CAM, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, EGP, Epithelial glycoprotein 314, hEGP314, KS 1/4 antigen, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, CD326, EPCAM, GA733-2, M1S2

Background: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Gene ID: 4072

UniProt: P16422