GLTPD2 antibody (Alexa Fluor 594)

Catalog No. ABIN2813797

Product Details anti-GLTPD2 Antibody (Alexa Fluor 594)

Target: GLTPD2 (Glycolipid Transfer Protein Domain Containing 2 (GLTPD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLTPD2 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLTPD2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GLTPD2

Target: GLTPD2 (Glycolipid Transfer Protein Domain Containing 2 (GLTPD2))

Alternative Name: GLTPD2 (GLTPD2 Products)

Synonyms: C730027E14Rik antibody, RP23-122P1.9 antibody, RGD1560459 antibody, glycolipid transfer protein domain containing 2 antibody, GLTPD2 antibody, Gltpd2 antibody

Background:

Synonyms: glycolipid transfer protein domain-containing protein 2, Glycolipid transfer protein domain containing 2, GLTD2_HUMAN.

Background: The GLTP (glycolipid transfer protein) superfamily is defined by a unique lipid transfer/binding fold (GLTP fold) that accelerate glycolipid intermembrane transfer. GLTPD2 is a 291 amino acid protein that belongs to the GLTP family. The gene encoding GLTPD2 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth are both linked to mutations on chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.