HCV NS5a antibody (Alexa Fluor 594)

Catalog No. ABIN2814260

Product Details anti-HCV NS5a Antibody (Alexa Fluor 594)

Target: HCV NS5a (Hepatitis C Virus NS5a (HCV NS5a))

Reactivity: Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCV NS5a antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Virus

Cross-Reactivity (Details): HCV

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Hepatitis C Virus NS5a

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HCV NS5a

Target: HCV NS5a (Hepatitis C Virus NS5a (HCV NS5a))

Alternative Name: Hepatitis C Virus NS5a (HCV NS5a Products)

Target Type: Viral Protein

Background:

Synonyms: HCV, HCV Non-structural protein 5A, Non-structural protein 5A, NS5a, p56, HCV NS5a, POLG_HCVBK.

Background: HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell.

UniProt: Q14SZ0