HRH4 antibody (AA 285-390) (Alexa Fluor 594)

Catalog No. ABIN2814512

Product Details anti-HRH4 Antibody (Alexa Fluor 594)

Target: HRH4 (Histamine Receptor H4 (HRH4))

Binding Specificity: AA 285-390

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH4 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HRH4/GPCR105

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HRH4

Target: HRH4 (Histamine Receptor H4 (HRH4))

Alternative Name: HRH4/GPCR105 (HRH4 Products)

Synonyms: AXOR35 antibody, BG26 antibody, GPCR105 antibody, GPRv53 antibody, H4 antibody, H4R antibody, HH4R antibody, HRH4 antibody, histamine receptor H4 antibody, HRH4 antibody, Hrh4 antibody

Background:

Synonyms: GPCR105, GPRv53, H4 antibody H4R, HH4R, Histamine H4 receptor, AXOR35, BG26, G protein coupled receptor 105, HRH4_HUMAN, SP9144.

Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.The Histamine H4 receptor has been reported in human blood peripheral leukocytes, bone marrow, colon, liver, lung, smalll intestine, spleen, testis, thymus, tonsil, and trachea.