PAK7 antibody (AA 168-198)

Catalog No. ABIN2842036

The Rabbit Polyclonal anti-PAK7 antibody is suitable to detect PAK7 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for PAK7 antibody (AA 168-198) (ABIN2842036)

Target: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1235

Product Details anti-PAK7 Antibody

Binding Specificity: AA 168-198

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PAK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from human PAK5.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PAK7

Target: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Alternative Name: PAK5

Background: PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.

Molecular Weight: 80745

Gene ID: 57144

NCBI Accession: NP_065074, NP_817127

UniProt: Q9P286