STRA6 antibody (C-Term)

Catalog No. ABIN653383

Product Details anti-STRA6 Antibody

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Binding Specificity: AA 586-614, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STRA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-614 AA from the C-terminal region of human STRA6.

Clone: RB25359

Isotype: Ig Fraction

Application Details

Application Notes: Suggested dilutions:
WB = 1:1000, IHC (p) = 1:50-100
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Expiry Date: 6 months

Target Details for STRA6

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Alternative Name: STRA6 (STRA6 Products)

Synonyms: MCOPCB8 antibody, MCOPS9 antibody, AI891933 antibody, RGD1307551 antibody, STRA6 antibody, im:7151282 antibody, wu:fc51h06 antibody, zgc:136689 antibody, mcops9 antibody, pp14296 antibody, stimulated by retinoic acid 6 antibody, stimulated by retinoic acid gene 6 antibody, stimulated by retinoic acid gene 6 homolog (mouse) antibody, STRA6 antibody, Stra6 antibody, stra6 antibody

Background: Function
May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity).

Cellular Location
Cell membrane, Multi-pass membrane protein (Potential)

Tissue Location
Broad expression. In adult eye expressed in sclera, retina, retinal pigment epithelium, and trabecular meshwork but not in choroid and iris

Synonyms: Stimulated by retinoic acid gene 6 protein homolog, UNQ3126/PRO10282/PRO19578, PP14296, STRA6

Molecular Weight: 73503 Da

Gene ID: 64220

UniProt: Q9BX79

Pathways: Feeding Behaviour