SOCS4 antibody (AA 227-254)

Catalog No. ABIN2845222

This Rabbit Polyclonal antibody specifically detects SOCS4 in WB, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SOCS4 antibody (AA 227-254) (ABIN2845222)

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31389

Product Details anti-SOCS4 Antibody

Binding Specificity: AA 227-254

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the Central region of human SOCS4.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SOCS4

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Alternative Name: SOCS4

Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 50623

Gene ID: 122809

NCBI Accession: NP_543143, NP_955453

UniProt: Q8WXH5

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway