ATF2 antibody (N-Term)

Catalog No. ABIN285007

This Sheep Polyclonal antibody specifically detects ATF2 . It exhibits reactivity toward Mammalian.

Quick Overview for ATF2 antibody (N-Term) (ABIN285007)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivity: Mammalian

Host: Sheep

Clonality: Polyclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: Please inquire

Product Details anti-ATF2 Antibody

Binding Specificity: N-Term

Purification: Protein G affinity chromatography

Immunogen: ATF2 antibody was raised in Sheep using ATF-2, N-terminal fragment GST-fusion protein as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Protein G purified and supplied in PBS, pH 7.5, with no preservatives added.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF2

Background: ATF2 is a tTranscriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades