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- Target See all Bcl-2 (BCL2) Antibodies
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Bcl-2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit Polyclonal antibody to BCL2 (apoptosis regulator Bcl-2)
Bcl-2 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Bcl-2. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product BCL2 Primary Antibody
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anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibodyBCL2 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Chicken, Bacteria WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 1-100) antibodyBCL2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibodyBCL2 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB04684 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D1 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 Reactivity: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Host: Mouse Monoclonal Bcl-2-100 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)BCL2 Reactivity: Human FACS Host: Mouse Monoclonal Bcl-2-100 PE
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reactivity: Human WB, IHC, StM Host: Rabbit Monoclonal BCL2-2210R unconjugated Recombinant Antibody
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: BCL2-transfected 293T
Validation: Orthogonal, Overexpression
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Alternative Name
- BCL2 apoptosis regulator (BCL2 Products)
- Background
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This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Cellular Localization: Mitochondrion outer membrane , Nucleus membrane , Endoplasmic reticulum membrane - Molecular Weight
- 26 kDa
- Gene ID
- 596
- UniProt
- P10415
- Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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