Integrin Alpha2b antibody (C-Term)

Catalog No. ABIN2854318

This Rabbit Polyclonal antibody specifically detects Integrin Alpha2b in WB. It exhibits reactivity toward Human.

Quick Overview for Integrin Alpha2b antibody (C-Term) (ABIN2854318)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin Alpha2b Antibody

Binding Specificity: C-Term

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (80 %)

Characteristics: Rabbit Polyclonal antibody to CD41
CD41 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human CD41. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: K562

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41

Background: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molecular Weight: 113 kDa

Gene ID: 3674

Pathways: Integrin Complex