Fibronectin 1 antibody (C-Term)

Catalog No. ABIN2854774

This Rabbit Polyclonal antibody specifically detects Fibronectin 1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Fibronectin 1 antibody (C-Term) (ABIN2854774)

Target: Fibronectin 1 (FN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibronectin 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Fibronectin 1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Fibronectin (fibronectin 1)
Fibronectin antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Fibronectin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.31 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Fibronectin 1

Target: Fibronectin 1 (FN1)

Alternative Name: fibronectin 1

Background: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molecular Weight: 263 kDa

Gene ID: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy