Endothelin-1 Receptor antibody (C-Term)

Catalog No. ABIN285478

This Sheep Polyclonal antibody specifically detects Endothelin-1 Receptor in IF, IHC, IP and IC. It exhibits reactivity toward Rat.It has been mentioned in 1 publication

Quick Overview for Endothelin-1 Receptor antibody (C-Term) (ABIN285478)

Target: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Reactivity: Rat

Host: Sheep

Clonality: Polyclonal

Conjugate: This Endothelin-1 Receptor antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunochromatography (IC)

Product Details anti-Endothelin-1 Receptor Antibody

Binding Specificity: C-Term

Specificity: This peptide sequence is used when generating the antibody and has no significant homology with UPC1 or UPC3. Predicted cross reactivity is based on rat, hamster at 100% and human, pig, bovine, canine at 86%.

Cross-Reactivity: Mouse (Murine)

Purification: purified

Immunogen: Endothelin A receptor antibody was raised in sheep using C-terminal peptide QEQNHNTERSSHK residues 410 - 422 of rat ET(A) Receptor conjugated to KLH as the immunogen.

Application Details

Application Notes: IC: 10-20 µg/mL, IF: 10-20 µg/mL, IHC: 10-20 µg/mL, IP: 20-40 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Protein G purified and supplied in PBS, pH 7.5.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

References for anti-Endothelin-1 Receptor antibody (ABIN285478)

Lampmann, Borger, Konczalla, Gispert, Auburger, Vatter, Güresir: "Experimental Induction of Intracranial Aneurysms in Rats: A New Model Utilizing a Genetic Modification within the EDNRA Gene." in: Brain sciences, Vol. 12, Issue 9, (2022) (PubMed).

Target Details for Endothelin-1 Receptor

Target: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Alternative Name: Endothelin A Receptor

Background: Endothelins are a family of peptides that are potent vasoconstrictors produced by mammalian vascular endothelial cells. The receptors for endothelins are widely expressed on tissues.

Pathways: cAMP Metabolic Process