PDCD6 antibody

Catalog No. ABIN2855317

This Rabbit Polyclonal antibody specifically detects PDCD6 in WB, IF, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PDCD6 antibody (ABIN2855317)

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDCD6 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to PDCD6 (programmed cell death 6)
PDCD6 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PDCD6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa nucleus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: programmed cell death 6

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.

Cellular Localization: Nucleus membrane, Peripheral membrane protein , Endoplasmic reticulum membrane, Peripheral membrane protein , Nucleus

Molecular Weight: 22 kDa

Gene ID: 10016

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity