Kallikrein 6 antibody

Catalog No. ABIN2855841

This anti-Kallikrein 6 antibody is a Rabbit Polyclonal antibody detecting Kallikrein 6 in ICC and IF. Suitable for Human.

Quick Overview for Kallikrein 6 antibody (ABIN2855841)

Target: Kallikrein 6 (KLK6)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 6 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Kallikrein 6 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to Kallikrein 6 (kallikrein-related peptidase 6)
Kallikrein 6 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.88 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Kallikrein 6

Target: Kallikrein 6 (KLK6)

Alternative Name: kallikrein related peptidase 6

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Cellular Localization: Secreted , Nucleus , nucleolus , Cytoplasm , Mitochondrion , Microsome

Molecular Weight: 27 kDa

Gene ID: 5653

UniProt: Q92876

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling