Endoplasmic Reticulum Protein 44 (ERP44) (Center) antibody

Details for Product No. ABIN2856411
Target
Binding Specificity
Center
11
4
3
2
2
1
1
1
Reactivity
Human
38
7
6
3
3
3
3
3
3
3
2
2
2
2
1
1
1
Host
Rabbit
24
8
7
Clonality
Polyclonal
Conjugate
Un-conjugated
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
26
18
10
10
8
3
1
1
1
Options
Immunogen Recombinant protein encompassing a sequence within the center region of human TXNDC4. The exact sequence is proprietary.
Isotype IgG
Cross-Reactivity Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Xenopus tropicalis
Cross-Reactivity (Details) Mouse (98 %), Pig (97 %), Rat (99 %), Xenopus laevis (83 %), Bovine (97 %), Xenopus tropicalis (86 %)
Characteristics Rabbit Polyclonal antibody to TXNDC4 (endoplasmic reticulum protein 44)
TXNDC4 antibody [C1C3]
Purification Purified by antigen-affinity chromatography.
Target
Alternative Name TXNDC4 (ERP44 Antibody Abstract)
Background Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.

Cellular Localization: Endoplasmic reticulum lumen
Molecular Weight 47 kDa
Gene ID 23071
Pathways Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome
Application Notes Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Comment

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Images
Image no. 1 for anti-Endoplasmic Reticulum Protein 44 (ERP44) (Center) antibody (ABIN2856411) WB Image Sample(30 ug whole cell lysate) A:A431, B:H1299 10% SDS PAGE antibody dilute...
Image no. 2 for anti-Endoplasmic Reticulum Protein 44 (ERP44) (Center) antibody (ABIN2856411) IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using T...