ERP44 antibody

Catalog No. ABIN2856411

Product Details anti-ERP44 Antibody

Target: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERP44 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to TXNDC4 (endoplasmic reticulum protein 44)
TXNDC4 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TXNDC4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ERP44

Target: ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))

Alternative Name: endoplasmic reticulum protein 44 (ERP44 Products)

Synonyms: PDIA10 antibody, TXNDC4 antibody, 1110001E24Rik antibody, AI849526 antibody, AL033348 antibody, Txndc4 antibody, BWK4 antibody, txndc4 antibody, zgc:77883 antibody, endoplasmic reticulum protein 44 antibody, ERP44 antibody, Erp44 antibody, erp44 antibody

Background: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.

Cellular Localization: Endoplasmic reticulum lumen

Molecular Weight: 47 kDa

Gene ID: 23071

UniProt: Q9BS26

Pathways: Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome