Crossover junction endonuclease EME1 (EME1) (Internal Region) antibody
Quick Overview for Crossover junction endonuclease EME1 (EME1) (Internal Region) antibody (ABIN2857081)
Target
See all Crossover junction endonuclease EME1 (EME1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Characteristics
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Rabbit Polyclonal antibody to EME1 (essential meiotic endonuclease 1 homolog 1 (S. pombe))
EME1 antibody [N3C2], Internal -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human EME1. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Comment
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Positive Control: HeLa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Crossover junction endonuclease EME1 (EME1)
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Alternative Name
- EME1
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Background
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EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM]
Cellular Localization: Nucleus , nucleolus -
Molecular Weight
- 63 kDa
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Gene ID
- 146956
Target
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