Proteasome 20S antibody

Catalog No. ABIN285927

Product Details

Target: Proteasome 20S

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse (Murine)

Purification: Purified

Immunogen: Proteasome 20 S antibody was raised in rabbit using a Mixture of synthetic peptides corresponding to residues C R(207) V I L G N/D E L P K F Y D E(220) of human and mouse proteasome 20 LMP2 as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified IgG supplied in PBS with 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details

Target: Proteasome 20S

Synonyms: PSC5 antibody, ZETA antibody, proteasome subunit alpha 5 antibody, proteasome (prosome, macropain) subunit, alpha type 5 antibody, PSMA5 antibody, Psma5 antibody

Background: LMP2 is a catalytic subunit of the 20S proteasome and, upon interferon gamma-induction, replaces the delta subunit. LMP2 alters the specificity of the 20S proteasome and is critical for the production of MHC class I ligands, production of T-lymphocytes, and is suggested to increase the efficiency of antigen presentation of the immune response.