H2AFX antibody (H2AK5ac)

Catalog No. ABIN7305452

The Rabbit Polyclonal anti-H2AFX antibody is suitable to detect H2AFX in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for H2AFX antibody (H2AK5ac) (ABIN7305452)

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-H2AFX Antibody

Binding Specificity: H2AK5ac

Purpose: Rabbit polyclonal antibody to Histone H2A.X (Acetyl-K5)

Specificity: Recognizes endogenous levels of Histone H2A.X protein only when acetylated at K5.

Characteristics: Rabbit polyclonal to Histone H2A.X (AcK5)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic acetylated peptide corresponding to residues surrounding K5 of human Histone H2A.X protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/1000 - 1/2000), IH (1/200 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for H2AFX

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Alternative Name: Histone H2A.X

Background: H2AX, Histone H2AX, H2a/x, Histone H2A.X

Gene ID: 3014, 15270

UniProt: P16104

Pathways: Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus