p53 antibody (acLys379)
Quick Overview for p53 antibody (acLys379) (ABIN2878849)
Target
See all p53 (TP53) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- acLys379
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Brand
- IHC-plus™
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Specificity
- P53 (Acetyl-Lys379) Antibody detects endogenous levels of total p53 protein only when acetylated at lysine379.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic peptide from human p53 around the acetylated site of Lys379.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
- Approved: IF (1:100 - 1:500), IHC, IHC-P (1:200), Peptide-ELISA (1:10000)
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Alternative Name
- TP53 / p53
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Background
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Name/Gene ID: TP53
Family: P53
Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1 -
Gene ID
- 7157
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UniProt
- P04637
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Pathways
- p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
Target
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