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p53 antibody (acLys379)

This Rabbit Polyclonal antibody specifically detects p53 in IHC, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN2878849

Quick Overview for p53 antibody (acLys379) (ABIN2878849)

Target

See all p53 (TP53) Antibodies
p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This p53 antibody is un-conjugated

Application

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

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    acLys379

    Brand

    IHC-plus™

    Specificity

    P53 (Acetyl-Lys379) Antibody detects endogenous levels of total p53 protein only when acetylated at lysine379.

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic peptide from human p53 around the acetylated site of Lys379.

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Application Notes

    Approved: IF (1:100 - 1:500), IHC, IHC-P (1:200), Peptide-ELISA (1:10000)

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    avoid freeze thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • Target

    p53 (TP53) (Tumor Protein P53 (TP53))

    Alternative Name

    TP53 / p53

    Background

    Name/Gene ID: TP53
    Family: P53

    Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

    Gene ID

    7157

    UniProt

    P04637

    Pathways

    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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