IRS1 antibody (pSer312)

Catalog No. ABIN2888448

The Rabbit Polyclonal anti-IRS1 antibody has been validated for WB, ELISA and IF. It is suitable to detect IRS1 in samples from Human, Mouse and Rat.

Quick Overview for IRS1 antibody (pSer312) (ABIN2888448)

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-IRS1 Antibody

Binding Specificity: pSer312

Specificity: IRS-1 (Phospho-Ser312) Antibody detects endogenous levels of IRS-1 only when phosphorylated at serine312.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from human IRS-1 around the phosphorylation site of Ser312.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:100 - 1:500), Peptide-ELISA (1:20000), WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for up to 1 year.

Expiry Date: 12 months

Target Details for IRS1

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Alternative Name: IRS1 / IRS-1

Background: Name/Gene ID: IRS1

Synonyms: IRS1, IRS-1, HIRS-1, Insulin receptor substrate 1

Gene ID: 3667

UniProt: P35568

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process