SLC22A6 antibody

Catalog No. ABIN289973

Product Details anti-SLC22A6 Antibody

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT1 by peptide affinity chromatography.

Immunogen: Partial peptide of Human Organic Anion Transporter 1(OAT1)

Application Details

Application Notes: Working dilution for immunohistochemistry 5ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for SLC22A6

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Alternative Name: Organic Anion Transporter 1(OAT1) (SLC22A6 Products)

Synonyms: HOAT1 antibody, OAT1 antibody, PAHT antibody, ROAT1 antibody, NKT antibody, Oat1 antibody, Orctl1 antibody, mOat1 antibody, slc22a6 antibody, zgc:77073 antibody, SLC22A6 antibody, Paht antibody, Roat1 antibody, nkt antibody, oat1 antibody, oat1-B antibody, paht antibody, roat1 antibody, slc22a6-B antibody, Slc22a6 antibody, solute carrier family 22 member 6 antibody, solute carrier family 22 (organic anion transporter), member 6 antibody, solute carrier family 22 (organic anion transporter), member 6, like antibody, Solute carrier family 22 member 6 antibody, solute carrier family 22 (organic anion transporter), member 6 S homeolog antibody, SLC22A6 antibody, Slc22a6 antibody, slc22a6l antibody, s22a6 antibody, slc22a6.S antibody

Background: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for theelimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Human Organic anion transporter 1(OAT1) encodes a 563 amino acid residue protein, and which ispredicted 12 putative membrane-spanning protein. Human OAT1 was found to be expressed predominantlyin the kidney and only weakly in the brain. OAT1 mediates the Na+-independent transport of organic anions,such as PAH (p-aminohippurate), cyclic nucleotides, prostanoides, dicaroxylates, and many anion drugs.This antibody has been proved to be useful for immunohistochemistry .

Pathways: Dicarboxylic Acid Transport